Main Line Health (MLH) is a not-for-profit health system serving Philadelphia and its western suburbs. Recognized for its commitment to compassionate care, MLH comprises five acute care hospitals: Lankenau Medical Center, Bryn Mawr Hospital, Paoli Hospital, Riddle Hospital, and Bryn Mawr Rehab Hospital. Additionally, it includes a vast network of outpatient health centers, physician practices, a home care division, and the Lankenau Institute for Medical Research. Main Line Health focuses on providing a comprehensive range of services, from primary and specialty care to advanced V_REPLACE_medical treatments, education, and research, all aimed at enhancing the health and wellness of the communities it serves.
Serves as the central administrative hub for the health system, overseeing strategic planning, financial operations, human resources, information technology, legal, marketing, and system-wide coordination for its hospitals and numerous outpatient facilities.
Located within the Radnor Corporate Center, a modern office park offering a professional environment with contemporary amenities and infrastructure. The facilities are designed to support efficient administrative operations.
The work culture at Main Line Health's headquarters is characterized by professionalism, collaboration, and a strong sense of mission focused on supporting the clinical operations and community health initiatives of the entire system. Employees often highlight a commitment to excellence and patient-centered values.
The headquarters is crucial for the integrated functioning of Main Line Health, enabling standardized practices, resource allocation, and strategic direction across its diverse healthcare entities, ensuring consistent quality and care delivery.
Main Line Health primarily serves the Greater Philadelphia region in southeastern Pennsylvania, USA. While its Lankenau Institute for Medical Research collaborates with researchers globally and its staff may participate in international conferences or initiatives, its direct healthcare services and operational footprint are concentrated within its regional U.S. locations. It does not operate hospitals or clinics internationally.
240 North Radnor Chester Road
Radnor
Pennsylvania
USA
Address: Lankenau Medical Center, 100 E Lancaster Ave, Wynnewood, PA 19096
Serves as a flagship hospital providing comprehensive inpatient and outpatient medical services, advanced specialty care, and a hub for medical education and research for the western Philadelphia region.
Address: Bryn Mawr Hospital, 130 S Bryn Mawr Ave, Bryn Mawr, PA 19010
Provides essential hospital services and specialized medical care to the residents of Bryn Mawr and surrounding communities, with a strong focus on community health and wellness programs.
Address: Paoli Hospital, 255 W Lancaster Ave, Paoli, PA 19301
Offers advanced medical and surgical care, emergency services including a Level II Trauma Center, and specialized programs to meet the healthcare needs of the western Main Line and Chester County.
Address: Riddle Hospital, 1068 W Baltimore Pike, Media, PA 19063
Functions as a community hospital delivering comprehensive medical services, emergency care, and specialized treatments to the population of Media and the broader Delaware County area.
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As of April 2025, Main Line Health' leadership includes:
Main Line Health has been backed by several prominent investors over the years, including:
In the past 12 months, Main Line Health has seen some leadership appointments within its key hospital entities. While major system-wide C-suite turnovers have not been prominently announced, strategic leadership placements continue to strengthen its operational capabilities. For example, Trish O’Keefe was appointed President of Paoli Hospital.
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Main Line Health commonly uses the email domain @mlhs.org for its employees. The most prevalent format appears to be the last name followed by the first initial.
[last][first_initial]@mlhs.org
Format
lynchj@mlhs.org
Example
85%
Success rate
Main Line Health Newsroom • February 13, 2024
Main Line Health announced that Trish W. O’Keefe, PhD, RN, has been named president of Paoli Hospital. O’Keefe has served in various leadership roles within Main Line Health, most recently as Chief Nursing Officer at Lankenau Medical Center....more
Main Line Health Newsroom • October 26, 2023
Main Line Health celebrated its annual Physicians of the Year awards, recognizing outstanding physicians across its hospitals for their dedication to patient care, medical excellence, and community service....more
U.S. News & World Report • September 7, 2023
Several Main Line Health hospitals, including Lankenau Medical Center, Bryn Mawr Hospital, and Paoli Hospital, received high-performing ratings in various specialties and conditions in the U.S. News & World Report 2023-2024 Best Hospitals rankings, underscoring their commitment to quality care....more
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