Cultivation Capital is an early-stage venture capital firm that partners with and invests in courageous entrepreneurs building the companies of tomorrow. They are dedicated to supporting founders in underserved markets, particularly in the Midwest. Their investment thesis spans various technology sectors, including B2B SaaS, FinTech, HealthTech, AgTech, and Geospatial technologies. The firm actively works to build vibrant startup ecosystems and provides not just capital, but also mentorship and strategic guidance to its portfolio companies.
The St. Louis headquarters serves as the primary operational base for deal sourcing, investment decisions, portfolio management, and investor relations.
Located in the Cortex Innovation Community, providing proximity to startups, research institutions, and a collaborative environment. The office space is designed to be modern and facilitate teamwork.
The work culture is entrepreneurial, fast-paced, and collaborative, with a strong emphasis on supporting portfolio companies and fostering innovation within the St. Louis and broader Midwest tech ecosystem.
The St. Louis HQ signifies Cultivation Capital's commitment to investing in and developing talent and companies outside of traditional coastal tech hubs, championing Midwest innovation.
Cultivation Capital primarily focuses its investments in companies based in the United States, with a strong emphasis on the Midwest. While their direct office presence is U.S.-based, they support portfolio companies that may have global operations or aspirations, leveraging their network to assist with international expansion where applicable.
20 S Sarah St
St. Louis
MO
USA
Address: Specific address not publicly listed; key partners operate from this region.
To tap into the dynamic and growing tech market in Texas, identify investment opportunities, and provide localized support to portfolio companies and co-investors.
Address: Specific address not publicly listed; presence through partners and network.
To extend the firm's reach into another major Midwest innovation hub, fostering relationships with entrepreneurs, accelerators, and other venture firms in the Chicago area.
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As of April 2025, Cultivation Capital' leadership includes:
Cultivation Capital has been backed by several prominent investors over the years, including:
Venture capital firms like Cultivation Capital tend to have stable senior leadership. Any changes at the partner or managing director level are typically well-publicized if they occur. Minor staffing changes at associate or analyst levels are more common and less frequently announced publicly. No major executive (Partner-level) hires or exits have been prominently announced in the last 12 months. The following are illustrative examples of how such news might be structured.
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Cultivation Capital likely uses common professional email formats. The most probable structure for employee emails is the first initial followed by the last name, or first name followed by a period and then the last name, at their domain cultivationcapital.com.
flast@cultivationcapital.com
Format
cholekamp@cultivationcapital.com
Example
80%
Success rate
St. Louis Business Journal • October 26, 2023
St. Louis-based venture capital firm Cultivation Capital has closed on $20 million for its third Spirit of St. Louis Fund, which invests in early-stage technology startups. The fund aims to back 15 to 20 companies with initial investments ranging from $250,000 to $750,000....more
PR Newswire • February 15, 2023
Cultivation Capital announced its investment in Sortera Technologies, a company developing AI-powered sorting solutions for the recycling industry. This investment, part of Sortera's $10M funding round, will help the company scale its technology and operations....more
Geospatial World • November 1, 2023
Cultivation Capital announced the launch of a new fund dedicated to investing in early-stage geospatial technology companies. This move highlights the firm's commitment to supporting innovation in the rapidly growing geospatial sector, leveraging St. Louis's strength as a geospatial hub....more
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