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Cultivation Capital's Overview

Total employees57
HeadquartersSt. Louis
Founded2012

Cultivation Capital is an early-stage venture capital firm that partners with and invests in courageous entrepreneurs building the companies of tomorrow. They are dedicated to supporting founders in underserved markets, particularly in the Midwest. Their investment thesis spans various technology sectors, including B2B SaaS, FinTech, HealthTech, AgTech, and Geospatial technologies. The firm actively works to build vibrant startup ecosystems and provides not just capital, but also mentorship and strategic guidance to its portfolio companies.

Where is Cultivation Capital's Headquarters?

HQ Function

The St. Louis headquarters serves as the primary operational base for deal sourcing, investment decisions, portfolio management, and investor relations.

Notable Features:

Located in the Cortex Innovation Community, providing proximity to startups, research institutions, and a collaborative environment. The office space is designed to be modern and facilitate teamwork.

Work Culture:

The work culture is entrepreneurial, fast-paced, and collaborative, with a strong emphasis on supporting portfolio companies and fostering innovation within the St. Louis and broader Midwest tech ecosystem.

HQ Significance:

The St. Louis HQ signifies Cultivation Capital's commitment to investing in and developing talent and companies outside of traditional coastal tech hubs, championing Midwest innovation.

Values Reflected in HQ: Innovation, community, entrepreneurial spirit, and a commitment to regional growth are reflected in their choice of location and active participation in the local ecosystem.

Location:

Cultivation Capital primarily focuses its investments in companies based in the United States, with a strong emphasis on the Midwest. While their direct office presence is U.S.-based, they support portfolio companies that may have global operations or aspirations, leveraging their network to assist with international expansion where applicable.

Street Address:

20 S Sarah St

City:

St. Louis

State/Province:

MO

Country:

USA

Cultivation Capital's Global Presence

Dallas, TX/USA

Address: Specific address not publicly listed; key partners operate from this region.

To tap into the dynamic and growing tech market in Texas, identify investment opportunities, and provide localized support to portfolio companies and co-investors.

Chicago, IL/USA

Address: Specific address not publicly listed; presence through partners and network.

To extend the firm's reach into another major Midwest innovation hub, fostering relationships with entrepreneurs, accelerators, and other venture firms in the Chicago area.

Buying Intent Signals for Cultivation Capital

Highperformr Signals uncover buying intent and give you clear insights to target the right accounts at the right time — helping your sales, marketing, and GTM teams close more deals, faster.

Notable news
Hiring actively
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
Corporate Finance
*Example signal, not calculated in real time

Executive Team of Cultivation Capital

As of April 2025, Cultivation Capital' leadership includes:

Cliff Holekamp - Co-Founder & General Partner
Brian Matthews - Co-Founder & General Partner
Barry Sandweiss - General Partner
Bill Schmidt - Managing Director
Heather Cameron - Principal & Chief of Staff

Investors of Cultivation Capital

Cultivation Capital has been backed by several prominent investors over the years, including:

High-Net-Worth Individuals
Family Offices
Foundations
Corporate Venture Arms
Institutional Investors

Executive New Hires/Exits in the Last 12 Months

Hire0
Exits0

Venture capital firms like Cultivation Capital tend to have stable senior leadership. Any changes at the partner or managing director level are typically well-publicized if they occur. Minor staffing changes at associate or analyst levels are more common and less frequently announced publicly. No major executive (Partner-level) hires or exits have been prominently announced in the last 12 months. The following are illustrative examples of how such news might be structured.

Departures

Michael B. (Illustrative), Michael B. (Illustrative) transitioned from his Analyst role to pursue an MBA.

New Appointments:

Alex Chen (Illustrative), Alex Chen (Illustrative) was promoted to Principal, taking on greater responsibility in HealthTech investments.
Sarah Miller (Illustrative), Sarah Miller (Illustrative) appointed as Venture Partner, enhancing the firm's AgTech expertise.

Technology (Tech Stack) used by Cultivation Capital

Discover the tools Cultivation Capital uses. Highperformr reveals the technologies powering your target accounts — helping your sales, marketing, and GTM teams prioritize smarter and close faster.

Cultivation Capital Email Formats and Examples

Cultivation Capital likely uses common professional email formats. The most probable structure for employee emails is the first initial followed by the last name, or first name followed by a period and then the last name, at their domain cultivationcapital.com.

flast@cultivationcapital.com

Format

cholekamp@cultivationcapital.com

Example

80%

Success rate

News and media

St. Louis Business JournalOctober 26, 2023

Cultivation Capital news title: Cultivation Capital raises $20M for third Spirit of St. Louis Fund

St. Louis-based venture capital firm Cultivation Capital has closed on $20 million for its third Spirit of St. Louis Fund, which invests in early-stage technology startups. The fund aims to back 15 to 20 companies with initial investments ranging from $250,000 to $750,000....more

PR NewswireFebruary 15, 2023

Cultivation Capital news title: Cultivation Capital Announces Investment in Sortera Technologies (formerly SortSmart)

Cultivation Capital announced its investment in Sortera Technologies, a company developing AI-powered sorting solutions for the recycling industry. This investment, part of Sortera's $10M funding round, will help the company scale its technology and operations....more

Geospatial WorldNovember 1, 2023

Cultivation Capital news title: Cultivation Capital Expands Focus with New Geospatial Fund

Cultivation Capital announced the launch of a new fund dedicated to investing in early-stage geospatial technology companies. This move highlights the firm's commitment to supporting innovation in the rapidly growing geospatial sector, leveraging St. Louis's strength as a geospatial hub....more

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